This study concerns the oxidation of n-hexane. It was conducted in continuous flow fused-silica jet-stirred reactor (JSR) at 10 atm and an equivalence ratio of 0.5. n-Hexane initial concentrations were (i) 2500 ppm with a mean residence time of 1.5 s and (ii) 1000 ppm with a mean residence time of 0.7 s; we operated in the cool-flame regime for temperatures ranging from 540 to 720K and 530 to 800K, respectively. Products were analyzed and quantified in the gas phase using gas chromatography (with flame ionization, thermal conductivity, and quadrupole mass spectrometry) and Fourier transform infrared spectrometry. Products of low-temperature oxidation were sampled in the JSR and trapped in acetonitrile for characterization using an Orbitrap Q-Exactive®. Flow injection analyses (FIA) and ultra-high pressure liquid chromatography (UHPLC) coupled with atmospheric pressure chemical ionization (APCI +/-modes)-high resolution mass spectrometry (HRMS) analyses were used to characterize hydroperoxides (C6H14O2), keto-hydroperoxides (C6H12O3, C3H6O3, C4H8O3, and C5H10O3), cyclic ethers (C6H12O), carboxylic acids (C2 to C6), ketones (C3 to C6), diones (C6H10O2), unsaturated ketones (C6H10O and C6H8O), unsaturated diones (C6H8O2), and highly oxygenated molecules (C6H12O4-8) produced by addition of three and four oxygen molecules on fuel's radicals. To confirm the presence of hydroxyl or hydroperoxyl groups in the oxidation products we used H/D exchange with D2O. 2,4-Dinitrophenylhydrazine (2,4-DNPH) derivatization was used to characterize and confirm the presence of different carbonyls which can be formed during the low temperature oxidation of n-hexane. An available kinetic reaction mechanism including 3 rd O2 addition on fuel's radicals was used to simulate the formation of the presently detected keto-hydroperoxides (KHP) and highly oxygenated molecules (HOMs).