Morpholino-functionalized phosphorus dendrimers for precision regenerative medicine: osteogenic differentiation of mesenchymal stem cells - Archive ouverte HAL
Article Dans Une Revue Nanoscale Année : 2019

Morpholino-functionalized phosphorus dendrimers for precision regenerative medicine: osteogenic differentiation of mesenchymal stem cells

Résumé

A novel bioactive macromolecule based on morpholino-functionalized phosphorus dendrimers (generation 2, G2-Mor+) was developed for osteogenic differentiation of mesenchymal stem cells (MSCs). Interestingly, through in vitro tests, it was shown that G2-Mor+ dendrimer can strongly promote the transformation of MSCs into osteoblasts, which implies the potential application of phosphorus dendrimers in bone regeneration for precision regenerative medicine.

Dates et versions

hal-03274505 , version 1 (30-06-2021)

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Citer

Aijun Li, Yu Fan, Xueyan Cao, Liang Chen, Le Wang, et al.. Morpholino-functionalized phosphorus dendrimers for precision regenerative medicine: osteogenic differentiation of mesenchymal stem cells. Nanoscale, 2019, 11 (37), pp.17230-17234. ⟨10.1039/C9NR06410A⟩. ⟨hal-03274505⟩
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