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Article Dans Une Revue World Allergy Organization Journal Année : 2020

IgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paper

1 Hospital Quirónsalud Bizkaia [Bilbao]
2 Hunimed - Humanitas University [Milan]
3 University of Cartagena
4 A.S.L. Vercelli
5 Sagamihara National Hospital [Kanagawa, Japan]
6 UniGe - Università degli studi di Genova = University of Genoa
7 Ospedale Policlinico San Martino [Genoa]
8 UZA - Antwerp University Hospital [Edegem]
9 Ucasal - Universidad Católica De Salta
10 Vall d'Hebron University Hospital [Barcelona]
11 Pulmonary and Allergy Associates
12 Vetmeduni - University of Veterinary Medicine [Vienna]
13 Fischer Medicine Professional Corporation
14 Helsingin yliopisto = Helsingfors universitet = University of Helsinki
15 UVSQ Santé - Université de Versailles Saint-Quentin-en-Yvelines - UFR Sciences de la santé Simone Veil
16 CHRU Montpellier - Centre Hospitalier Régional Universitaire [Montpellier]
17 INSERM - Institut National de la Santé et de la Recherche Médicale
18 EUFOREA - European Forum for Research and Education in Allergy and Airway Diseases
19 UAB - Universitat Autònoma de Barcelona = Autonomous University of Barcelona = Universidad Autónoma de Barcelona
20 Chiang Children's Allergy & Asthma Clinic
21 UFR 927 - Sorbonne Université - UFR Sciences de la vie
22 Immunology Research Institute of New England
23 Unidad de Educación Médica
24 Erasmus MC - Erasmus University Medical Center [Rotterdam]
25 UANL - Universidad Autonoma de Nuevo Leon [Mexique]
26 Mayo Clinic [Jacksonville]
27 University of Kirikkale
28 USP - Universidade de São Paulo = University of São Paulo
29 MUL - Medical University of Łódź
30 USF - University of South Florida [Tampa]
31 National University of Costa Rica
32 Hospital CUF Descobertas
33 Philipps Universität Marburg = Philipps University of Marburg
34 University Hospital Herlev Gentofte
35 Nippon Medical School [Tokyo, Japon]
36 Stallergenes - Stallergenes SA
37 UTFPR - Universidade Tecnológica Federal do Paraná [Curitiba, Brasil] = Federal Technological University of Paraná [Curitiba, Brazil] = Université technologique fédérale du Paraná [Curitiba, Brésil]
38 University of Missouri School of Medicine
39 Centro Médico Docente La Trinidad
40 IDI-IRCCS - Istituto dermopatico dell'immacolata
41 Ospedale Civile Maggiore
42 Clínica de alergía y asma
43 Royal Children’s Hospital & Department of Paediatrics [Parkville, VIC, Australia]
44 Tan Tock Seng Hospital
45 Medizinische Universität Wien = Medical University of Vienna
46 Sechenov First Moscow State Medical University
47 Johns Hopkins University School of Medicine [Baltimore]
48 Charité Campus Mitte
Giorgio Walter Canonica
Elisa Villa
  • Fonction : Auteur
Martti Antila
  • Fonction : Auteur
Alexei Gonzalez-Estrada
Edgardo José Jares
  • Fonction : Auteur
Antonino G. Romano
Enrico Scala
Gianenrico Senna
Torsten Zuberbier

Résumé

Currently, testing for immunoglobulin E (IgE) sensitization is the cornerstone of diagnostic evaluation in suspected allergic conditions. This review provides a thorough and updated critical appraisal of the most frequently used diagnostic tests, both in vivo and in vitro. It discusses skin tests, challenges, and serological and cellular in vitro tests, and provides an overview of indications, advantages and disadvantages of each in conditions such as respiratory, food, venom, drug, and occupational allergy. Skin prick testing remains the first line approach in most instances; the added value of serum specific IgE to whole allergen extracts or components, as well as the role of basophil activation tests, is evaluated. Unproven, non-validated, diagnostic tests are also discussed. Throughout the review, the reader must bear in mind the relevance of differentiating between sensitization and allergy; the latter entails not only allergic sensitization, but also clinically relevant symptoms triggered by the culprit allergen.
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hal-03228161 , version 1 (10-06-2021)

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Ignacio Javier Ansotegui, Giovanni G. Melioli, Giorgio Walter Canonica, Luis R. Caraballo, Elisa Villa, et al.. IgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paper. World Allergy Organization Journal, 2020, 13 (2), ⟨10.1016/j.waojou.2019.100080⟩. ⟨hal-03228161⟩
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