The global aviation industry adopted a set of targets to mitigate CO2 emissions resulting from air transportation in 2009. The engine fuel burn is the main driver of CO2 emission; hence it will be the focus of this study. Rotorcraft are designed for supporting different types of missions or operations that are different from fixed wing aircraft. For this reason, the rotorcraft strategy for addressing the carbon impact should mainly target the new emerging technologies that will assist in reducing the fuel consumption and the deployment of Sustainable Aviation Fuels (SAF). This paper presents a forecast of the contribution level that could be achieved by rotorcraft industry in CO2 emission reduction in the period up to 2050. A projection of growth in civil rotorcraft fleet worldwide is provided as the starting point. Several new emerging technologies for both rotorcraft and engine together with the implementation scheme and their projected positive net impact on CO2 emission level are considered. Further, the contribution from SAF deployment in rotorcraft operation is analyzed. It is generally recognized that as much as 80% reduction in overall CO2 life cycle emission can be achieved from SAF relative to the fossil-based fuels or Conventional Aviation Fuels (CAF). However, some critical parameters used in predicting the SAF benefits remain uncertain. These pertain to fuel resources, economy, investment and policies. Therefore, consistent with previous studies, several fuel substitution scenarios are considered ranging from the most conservative to an optimistic projection.