The aim of our project was to investigate on the book trade during the Renaissance. It had focused on the relations between France and the Low Countries which have never been the subject of systematic analysis. The study of the book market is not only a chapter of economic history; it is also an accurate point of view to think about the most fundamental cultural trajectories. As a consequence, the ambition of this project was to renew our knowledge of cultural exchanges between France and the Low Countries through the study of the circulation of books between these two territories.