With the goal of ensuring the security of passengers for automotive industry, the present work addresses the ductile fracture process of plasticized PVC. Dedicated clamped single edge notch bending (SENB) specimens were used to characterize the mechanisms of crack initiation and propagation for the studied material. The exploitation of the experimental database associated with finite element simulation of the crack propagation allowed, on the one hand, the calibration factor η_p of this specific SENB specimen to be established, as a function of the crack depth ratio. On the other hand, the fracture toughness of the studied plasticized PVC was estimated to be 10.8 kJ/m², value which was close to that reported in the literature for modified PVC. By using this fracture toughness value, a methodology aiming at the prediction of ductile crack initiation of the PVC skin integrated into a real dashboard (full scale test) was proposed.