Hydrogen production by Rhodobacter capsulatus is an anaerobic, photobiological process requiring specific mixing conditions. In this study, an innovative design of a photobioreactor is proposed. The design is based on a plate-type photobioreactor with an interconnected meandering channel to allow culture mixing and H-2 degassing. The culture flow was characterized as a quasi-plug-flow with radial mixing caused by a turbulent-like regime achieved at a low Reynolds number. The dissipated volumetric power was decreased 10-fold while maintaining PBR performances (production and yields) when compared with a magnetically stirred tank reactor. To increase hydrogen production flow rate, several bacterial concentrations were tested by increasing the glutamate concentration using fed-batch cultures. The maximum hydrogen production flow rate (157.7 +/- 9.3 ml H-2/L/h) achieved is one of the highest values so far reported for H-2 production by R. capsulatus. These first results are encouraging for future scale-up of the plate-type reactor.