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Article Dans Une Revue Journal of Cardiothoracic Surgery Année : 2015

Is Seprafilm Valuable in Infant Cardiac Redo Procedures?

Résumé

BACKGROUND: Morbidity and mortality are higher for cardiac reoperations than first operation due to the presence of post-operative adhesions. We retrospectively evaluated the efficacy of the bioresorbable membrane Seprafilm to prevent pericardial adhesions after cardiac surgery in a paediatric congenital heart disease population. METHODS: Seventy-one children undergoing reoperations with sternotomy redo and cardiopulmonary bypass for congenital malformations were included. Twenty-nine of these patients were reoperated after previous application of Seprafilm (treatment group). The duration of dissection, aortic cross clamping and total surgery were recorded. A tenacity score was established for each intervention from the surgeon's description in the operating report. RESULTS: In multivariate analysis, the duration of dissection and the tenacity score were lower in the treatment than control group (p\,<\,0.01), independent of age and interval since preceding surgery. CONCLUSION: Our results suggest that Seprafilm is effective in reducing the post-operative adhesions associated with infant cardiac surgery. We recommend the use of Seprafilm in paediatric cardiac surgery when staged surgical interventions are necessary.

Dates et versions

hal-03156116 , version 1 (02-03-2021)

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Bruno Lefort, Jean-Marc El Arid, Anne-Lorraine Bouquiaux, Nathalie Soulé, Julie Chantreuil, et al.. Is Seprafilm Valuable in Infant Cardiac Redo Procedures?. Journal of Cardiothoracic Surgery, 2015, 10, pp.47. ⟨10.1186/s13019-015-0257-2⟩. ⟨hal-03156116⟩
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