Mechanical control of morphogenetic robustness in an inherently challenging environment - Archive ouverte HAL Access content directly
Preprints, Working Papers, ... Year : 2021

Mechanical control of morphogenetic robustness in an inherently challenging environment

Emmanuel Martin
Sophie Theis
  • Function : Author
  • PersonId : 1147027
  • IdRef : 263400638
Guillaume Gay
Magali Suzanne

Abstract

Epithelial sheets undergo highly reproducible remodeling to shape organs. This stereotyped morphogenesis depends on a well-defined sequence of events leading to the regionalized expression of developmental patterning genes that finally triggers downstream mechanical forces to drive tissue remodeling at a pre-defined position. However, how tissue mechanics controls morphogenetic robustness when challenged by intrinsic perturbations in close proximity has never been addressed.

Dates and versions

hal-03101959 , version 1 (07-01-2021)

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Emmanuel Martin, Sophie Theis, Guillaume Gay, Bruno Monier, Christian Rouvière, et al.. Mechanical control of morphogenetic robustness in an inherently challenging environment. 2021. ⟨hal-03101959⟩
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