Signals and calcium waves at fertilization
Résumé
The study of sperm egg interactions and the signals they trigger, have made remarkable progress from the time of the seminal discovery of calcium waves 30 years ago. In this special issue of Seminars in Cell and Developmental Biology, 3 short pieces and 10 expert reviews survey this recent past and brings us up to date with current developments in this fertile field. Jaffe, Steinhardt and Whitaker recall the historical years while Miyazaki, Dumas, Rubinstein, Swann, Fissore, Sato, Foltz, Stricker, and their co-authors bring us up to date with current developments in sperm egg interaction, egg activation and calcium signalling. Dumollard, Duchen and Sardet and Ducibella, Schultz and Ozil deal with the pleiotropic consequences of stereotyped calcium signals from the cytoplasmic and cortical reorganizations they trigger including the stimulation of mitochondrial respiration, cell cycle regulation, the activation of protein synthesis, and subsequent developmental events. A list of interesting web sites giving access to video archives of fertilization and calcium waves is also provided.
Domaines
Biologie cellulaire
Origine : Accord explicite pour ce dépôt