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Article Dans Une Revue Chemical Society Reviews Année : 2020

Fluorescent glycoconjugates and their applications

Kai-Cheng Yan
  • Fonction : Auteur
Xi-Le Hu
  • Fonction : Auteur
Guo-Rong Chen
  • Fonction : Auteur
Xiao-Peng He
  • Fonction : Auteur
Sébastien Vidal

Résumé

Glycoconjugates and their applications as lectin ligands in biology has been thoroughly investigated in the past decades. Meanwhile, the intrinsic properties of such multivalent molecules were limited essentially to their ability to bind to their receptors with high selectivity and/or avidity. The present review will focus on multivalent glycoconjugates displaying an additional capability such as fluorescence properties for applications toward imaging of cancer cells, detection of proteins or pathogens but also for drug delivery systems toward targeted cancer therapy. This review is a collection of research articles discussed in the context of the structural features of the fluorescent glycoconjugates organized according to their fluorescent core scaffold and with their representative applications.
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Dates et versions

hal-03006696 , version 1 (23-11-2020)

Identifiants

Citer

Baptiste Thomas, Kai-Cheng Yan, Xi-Le Hu, Marion Donnier-Maréchal, Guo-Rong Chen, et al.. Fluorescent glycoconjugates and their applications. Chemical Society Reviews, 2020, 49 (2), pp.593-641. ⟨10.1039/C8CS00118A⟩. ⟨hal-03006696⟩
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