Membrane lipids are often viewed as passive building blocks of the endomembrane system. However, mounting evidence suggests that sphingolipids, sterols, and phospholipids are specifically targeted by developmental pathways, notably hormones, in a cell- or tissue-specific manner to regulate plant growth and development. Targeted modifications of lipid homeostasis may act as a way to execute a defined developmental program, for example, by regulating other signaling pathways or participating in cell differentiation. Furthermore, these regulations often feed back on the very signaling pathway that initiates the lipid metabolic changes. Here, we review several recent examples highlighting the intricate feedbacks between membrane lipid homeostasis and plant development. In particular, these examples illustrate how all aspects of membrane lipid metabolic pathways are targeted by these feedback regulations. We propose that the time has come to consider membrane lipids and lipid metabolism as an integral part of the developmental program needed to build a plant.