With the advent of the industrial revolution, human beings have developed drastically over the past decades. By 2020, wireless communications would connect more than twenty-five billion devices. Low Power Wide Area (LPWA) technologies are becoming popular as a result of the fast development of the Internet of Things (IoT) market. In this paper, we propose a wearable LoRa-based system for remote safety monitoring of people performing activities in remote areas with no network coverage. The designed system is supposed to detect possible heart problems and/or a “man-down” situation. It then transmits an emergency alert containing information about the state of the concerned individual and its location via LoRa to the surrounding recipients. The proposed system composed of a GPS enabled IoT device, a smart-watch and a smart-phone, has been validated in a remote area in the city of Belfort in France. The obtained results demonstrate the feasibility of such a system.