beta-C(sp2)-H Alkylation of enamides using xanthate chemistry
Résumé
Access to the γ-amino-β,γ-unsaturated acyl scaffold was established by applying xanthate chemistry to enamides. This original β-C(sp2)–H alkylation is regioselective and exhibits broad substrate scope and good functional group tolerance. The large availability of xanthates is advantageous to the scope of the reaction which combines a radical process and a polar reaction.
Origine | Fichiers produits par l'(les) auteur(s) |
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