Effect of early hyperoxemia on the outcome in servere blunt chest trauma: A propensity score-based analysis of a single-center retrospective cohort - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Journal of Critical Care Année : 2021

Effect of early hyperoxemia on the outcome in servere blunt chest trauma: A propensity score-based analysis of a single-center retrospective cohort

Baptiste Maille
Marie Wilkin
  • Fonction : Auteur
Matthieu Million
Frédéric Franceschi
Linda Koutbi-Franceschi
  • Fonction : Auteur
Jérôme Hourdain
  • Fonction : Auteur
Elisa Martinez
  • Fonction : Auteur
Maxime Zabern
  • Fonction : Auteur
Christophe Gardella
  • Fonction : Auteur
Hervé Tissot-Dupont
  • Fonction : Auteur
Jagmeet Singh
  • Fonction : Auteur
Jean-Claude Deharo
Laurent Fiorina
  • Fonction : Auteur

Résumé

Purpose Our study aimed to explore the association between early hyperoxemia of the first 24 h on outcomes in patients with severe blunt chest trauma. Materials and methods In a level I trauma center, we conducted a retrospective study of 426 consecutive patients. Hyperoxemic groups were classified in severe (average PaO2 ≥ 200 mmHg), moderate (≥150 and < 200 mmHg) or mild (≥ 100 and < 200 mmHg) and compared to control group (≥60 and < 100 mmHg) using a propensity score based analysis. The first endpoint was the incidence of a composite outcome including death and hospital-acquired pneumonia occurring from admission to day 28. The secondary endpoints were the incidence of death, the number of hospital-acquired pneumonia, mechanical ventilation-free days and intensive care unit-free day at day 28. Results The incidence of the composite endpoint was lower in the severe hyperoxemia group(OR, 0.25; 95%CI, 0.09–0.73; P < 0.001) compared with control. The 28-day mortality incidence was lower in severe (OR, 0.23; 95%CI, 0.08–0.68; P < 0.001) hyperoxemia group (OR, 0.41; 95%CI, 0.17–0.97; P = 0.04). Significant association was found between hyperoxemia and secondary outcomes. Conclusion In our cohort early hyperoxemia during the first 24 h of admission after severe blunt chest trauma was not associated with worse outcome.
Fichier principal
Vignette du fichier
2020 Duclos et al., Effect of.pdf (27.59 Mo) Télécharger le fichier
Origine Fichiers produits par l'(les) auteur(s)

Dates et versions

hal-02941991 , version 1 (14-10-2020)

Identifiants

Citer

Gary Duclos, Adrien Rivory, Noémie Rességuier, Emmanuelle Hammad, Coralie Vigne, et al.. Effect of early hyperoxemia on the outcome in servere blunt chest trauma: A propensity score-based analysis of a single-center retrospective cohort. Journal of Critical Care, 2021, 63, pp.179-186. ⟨10.1016/j.jcrc.2020.09.008⟩. ⟨hal-02941991⟩
78 Consultations
77 Téléchargements

Altmetric

Partager

Gmail Mastodon Facebook X LinkedIn More