Selective preparation of tetrasubstituted fluoroalkenes by fluorine-directed oxetane ring-opening reactions - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Beilstein Journal of Organic Chemistry Année : 2020

Selective preparation of tetrasubstituted fluoroalkenes by fluorine-directed oxetane ring-opening reactions

Résumé

The selective ring-opening reaction of fluoroalkylidene-oxetanes was directed by the presence of the fluorine atom, enabling a two-step access to tetrasubstituted fluoroalkenes with excellent geometry control. Despite its small van der Waals radii electronic, rather than steric influences of the fluorine atom governed the ring-opening reaction with bromide ions, even in the presence of bulky sub-stituents. 1936

Dates et versions

hal-02922851 , version 1 (31-08-2020)

Identifiants

Citer

Clément Fontenelle, Thibault Thierry, Romain Laporte, Emmanuel Pfund, Thierry Lequeux. Selective preparation of tetrasubstituted fluoroalkenes by fluorine-directed oxetane ring-opening reactions. Beilstein Journal of Organic Chemistry, 2020, 16, pp.1936 - 1946. ⟨10.3762/bjoc.16.160⟩. ⟨hal-02922851⟩
37 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More