Article Dans Une Revue Angewandte Chemie International Edition Année : 2020

Enantioselective Synthesis of Atropisomers with Multiple Stereogenic Axes

Résumé

Atropisomers possessing multiple stereogenic axes are intriguing molecules with huge potential. However, only few approaches for their enantioselective synthesis are available due to the difficulties in assembling various stereogenic axes with high enantiocontrol. Only recently, innovative methods have emerged, opening new possibilities for the synthesis of this original class of atropisomeric compounds. This Minireview describes the development of this field based on a classification of the multi-axis systems according to the distance between the stereogenic axes and the strategy used to build them.

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Est décrite par hal-02905420 Image Xiaoze Bao, Jean Rodriguez, Damien Bonne. Enantioselective Synthesis of Atropisomers with Multiple Stereogenic Axes. Illustration. France. 2019. ⟨hal-02905420⟩

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hal-02905416 , version 1 (23-07-2020)

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Xiaoze Bao, Jean Rodriguez, Damien Bonne. Enantioselective Synthesis of Atropisomers with Multiple Stereogenic Axes. Angewandte Chemie International Edition, 2020, 59 (31), pp.12623-12634. ⟨10.1002/anie.202002518⟩. ⟨hal-02905416⟩
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