Acetylcholine Delays Atrial Activation to Facilitate Atrial Fibrillation
Acetylcholine Delays Atrial Activation to Facilitate Atrial Fibrillation.
Résumé
Acetylcholine (ACh) shortens action potential duration (APD) in human atria. APD shortening facilitates atrial fibrillation (AF) by reducing the wavelength for reentry. However, the influence of ACh on electrical conduction in human atria and its contribution to AF are unclear, particularly when combined with impaired conduction from interstitial fibrosis.