Frozen Density Embedding (FDE) represents a versatile embedding scheme to describe the environmental effect on the electron dynamics in molecular systems. The extension of the general theory of FDE to the real-time time-dependent Kohn-Sham method has previously been presented and implemented in plane-waves and periodic boundary conditions (Pavanello et al. J. Chem. Phys. 142, 154116, 2015). In the current paper, we extend our recent formulation of real-time time-dependent Kohn-Sham method based on localized basis set functions and developed within the Psi4NumPy framework (De Santis et al. J. Chem. Theory Comput. 2020, 16, 2410) to the FDE scheme. The latter has been implemented in its "uncoupled" flavor (in which the time evolution is only carried out for the active subsystem, while the environment subsystems remain at their ground state), using and adapting the FDE implementation already available in the PyEmbed module of the scripting framework PyADF. The implementation was facilitated by the fact that both Psi4NumPy and PyADF, being native Python API, provided an ideal framework of development using the Python advantages in terms of code readability and reusability. We demonstrate that the inclusion of the FDE potential does not introduce any numerical instability in time propagation of the density matrix of the active subsystem and in the limit of weak external field, the numerical results for low-lying transition energies are consistent with those obtained using the reference FDE calculations based on the linear response TDDFT. The method is found to give stable numerical results also in the presence of strong external field inducing non-linear effects.