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Article Dans Une Revue Acta Ophthalmologica Scandinavica -Supplement- Année : 1992

Gentamicin, norfloxacin and lysozyme concentration in human tears: in vivo and in vitro study

Résumé

Hen's egg lysozyme (HEL) activity was measured in vitro with gentamicin and norfloxacin by a turbidimetric technique. Gentamicin at the concentration of 10(-3) M inhibited HEL activity by 39%, while 10(-3) M norfloxacin did not affect HEL activity. However, an in vivo study in healthy persons did not show any significant statistical difference in tear lysozyme activity when 0.3% gentamicin or 0.3% norfloxacin were topically applied.
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Dates et versions

hal-02712086 , version 1 (01-06-2020)

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  • HAL Id : hal-02712086 , version 1
  • PRODINRA : 458130
  • PUBMED : 1488882
  • WOS : A1992KF66800009

Citer

Alain M. Bron, C. Bonnin, Catherine Garcher, A. Lallemand. Gentamicin, norfloxacin and lysozyme concentration in human tears: in vivo and in vitro study. Acta Ophthalmologica Scandinavica -Supplement-, 1992, 70 (6), pp.750-753. ⟨hal-02712086⟩

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