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Article Dans Une Revue Data in Brief Année : 2017

Data on atherosclerosis specific antibody conjugation to nanoemulsions

Résumé

This article present data related to the publication entitled "Iron oxide core oil-in-water nanoemulsion as tracer for atherosclerosis MPI and MRI imaging" (Prévot et al., 2017) [1]. Herein we describe the engineering in the baculovirus-insect cell system and purification processes of the human scFv-Fc TEG4-2C antibody, specific of platelets within the atheroma plaque. For molecular targeting purpose, atheroma specific antibody was conjugated to nanoemulsions (NEs) using a heterobifunctional linker (DSPE-PEG-maleimide). Atheroma labelling was assayed by immunochemistry on arterial sections from rabbits.

Domaines

Biotechnologies
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Dates et versions

hal-02414267 , version 1 (16-12-2019)

Identifiants

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Geoffrey Prévot, Martine Duonor-Cerutti, Mélusine Larivière, Jeanny Laroche-Traineau, Marie Josée Jacobin-Valat, et al.. Data on atherosclerosis specific antibody conjugation to nanoemulsions. Data in Brief, 2017, 15, pp.824-827. ⟨10.1016/j.dib.2017.10.058⟩. ⟨hal-02414267⟩
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