Distinct RhoGEFs Activate Apical and Junctional Contractility under Control of G Proteins during Epithelial Morphogenesis
Résumé
Graphical Abstract Highlights d Dp114RhoGEF activates junctional Rho1 and is involved in cell intercalation d Ga/Cta and Gbg subunits tune, respectively, RhoGEF2 and Dp114RhoGEF membrane levels d Gbg subunits control planar polarity of junctional Rho1 signaling via Dp114RhoGEF d Tissue-specific RhoGEFs could diversify morphogenesis in different tissues
Domaines
Sciences du Vivant [q-bio]
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Distinct RhoGEFs Activate Apical and Junctional Contractility under Control of G Proteins during Epithelial MorphogenesisPIIS0960982219310334.pdf (9.97 Mo)
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