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Global responses to microstimulation at 7T and comparison with vibrotactile stimulation

Abstract

PURPOSE: Intra-neural microstimulation (INMS) is a technique that allows the precise delivery of low-current electrical pulses into human peripheral nerves. Single unit INMS can be used to stimulate individual afferent nerve fibres during microneurography. Combining INMS with neuroimaging 1,2 allows the unique monitoring of central nervous system activation in response to unitary, controlled tactile input, with functional magnetic resonance imaging (fMRI) providing high spatial localisation and sensitivity to brain activity. Here, we report the application of INMS at ultra-high field (7T), and compare the global pattern of positive and negative BOLD response to INMS with that of perceptually matched vibrotactile stimulation of the skin.

Domains

Neuroscience
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Dates and versions

hal-02357525 , version 1 (10-11-2019)

Identifiers

  • HAL Id : hal-02357525 , version 1

Cite

Ayan Sengupta, Rochelle Ackerley, Roger H. Watkins, Rosa Sanchez Panchuelo, Glover Paul, et al.. Global responses to microstimulation at 7T and comparison with vibrotactile stimulation. International Society for Magnetic Resonance in Medicine, Jun 2018, Paris, France. ⟨hal-02357525⟩
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