Short total syntheses of the avenaciolide family of natural products - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Tetrahedron Année : 2018

Short total syntheses of the avenaciolide family of natural products

Résumé

The avenaciolide family of natural products are small α-methylene bis-γ-lactones that exhibit a wide variety of biological activities. Herein we report concise syntheses of five members of this family of natural products along with the synthesis of one non-natural analogue. The syntheses proceed in five or six steps from simple, commercially available compounds and feature a key oxidative cyclization/lactonization reaction that likely occurs via a radical mechanism.
Fichier non déposé

Dates et versions

hal-02351390 , version 1 (06-11-2019)

Identifiants

Citer

Sandra Ainsua Martinez, Martin Gillard, Anne-Caroline Chany, Jonathan Burton. Short total syntheses of the avenaciolide family of natural products. Tetrahedron, 2018, 74 (38), pp.5012-5021. ⟨10.1016/j.tet.2018.06.028⟩. ⟨hal-02351390⟩
20 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More