Assembly and Characterizations of Bifunctional Fluorescent and Magnetic Microneedles Displaying Length Tunability over One Decade
Résumé
We report on the fabrication of bifunctional magnetic and fluorescent microneedles (µNDs) made of a ternary mixture of magnetic nanoparticles (NPs), quantum dots (QDs) and polyelectrolyte. The assembly relies on the electrostatic complexation of negatively charged NPs with positively charged polymer strands and is controlled by the charge ratio between the nanoparticulate building blocks and the polymer mortar. We show that the resulting µNDs retain the fluorescent and superparamagnetic ú gaelle.charron@univ-paris-diderot.fr1 properties of their NP constituents. Moreover, using a combination of core and surface characterisations and a state-of-the-art image analysis algorithm, we thoroughly investigate the dependence of the brightness and length on the ternary composition. In particular, based on statistics on hundreds of µNDs with a range of compositions, we show that the length can be robustly tuned over one decade to match the relevant length scales of various applications.
Origine : Fichiers produits par l'(les) auteur(s)
Loading...