Structural Basis for NusA Stabilized Transcriptional Pausing - Archive ouverte HAL Access content directly
Journal Articles Molecular Cell Year : 2018

Structural Basis for NusA Stabilized Transcriptional Pausing

Abstract

Highlights d Two cryo-EM reconstructions of paused RNAP elongation complexes bound by NusA d NusA provides positively charged cavity for RNA structures and stabilizes pause d Asymmetric translocation intermediate explains transcriptional pausing d Dynamic process of pausing reflected by RNAP global conformational changes
Fichier principal
Vignette du fichier
2018-guo.pdf (4.68 Mo) Télécharger le fichier
Origin : Publication funded by an institution

Dates and versions

hal-02342277 , version 1 (04-01-2021)

Identifiers

Cite

Xieyang Guo, Alexander G. Myasnikov, James Chen, Corinne Crucifix, Gabor Papai, et al.. Structural Basis for NusA Stabilized Transcriptional Pausing. Molecular Cell, 2018, 69 (5), pp.816-827.e4. ⟨10.1016/j.molcel.2018.02.008⟩. ⟨hal-02342277⟩
25 View
56 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More