Signal Transduction: IMPlications for Ras-Dependent ERK Signaling
Résumé
Ras interacts with numerous downstream effectors to transmit a diverse array of cellular signals. A new study shows that a protein known as Impedes Mito-genic signal Propagation, IMP, is an E3 ubiquitin ligase that binds Ras and modulates MAP kinase sig-naling by regulating the scaffolding activity of KSR.
Domaines
Réseaux moléculaires [q-bio.MN]
Origine : Fichiers éditeurs autorisés sur une archive ouverte
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