Voltammetric Sensor Based on a Double-Layered Molecularly Imprinted Polymer for Testosterone - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Analytical Letters Année : 2017

Voltammetric Sensor Based on a Double-Layered Molecularly Imprinted Polymer for Testosterone

Résumé

A novel strategy to improve the sensitivity of molecularly imprinted polymer sensors based on a double-layered molecularly imprinted polymer hybrid film-modified gold electrode was investigated for the determination of testosterone. A conductive poly(anilinomethyltriethoxysilane) film was electrodeposited on the surface of the electrode, and a molecularly imprinted polysiloxane thin film was formed on the conductive layer by a sol-gel process to enhance the electrochemical response. The performance of the sensor for testosterone was investigated by square-wave voltammetry in the presence of a hexacyanoferrate/ferrite as a redox probe. The prepared sensor provided high recognition for testosterone with a broad linear range from 10 to 100fM and a low detection limit of 10fM. Good sensitivity, selectivity, and stability were observed with relative standard deviations less than 5%. Good recovery of testosterone was obtained when the sensor was used for the determination of testosterone in fortified urine.
Fichier non déposé

Dates et versions

hal-02116237 , version 1 (30-04-2019)

Identifiants

Citer

Hana Fourou, Mohamed Braiek, Anne Bonhommé, Florence Lagarde, Ali Zazoua, et al.. Voltammetric Sensor Based on a Double-Layered Molecularly Imprinted Polymer for Testosterone. Analytical Letters, 2017, 51 (3), pp.312-322. ⟨10.1080/00032719.2017.1298118⟩. ⟨hal-02116237⟩
29 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More