Biorthogonal click chemistry on poly(lactic-co-glycolic acid)-polymeric particles - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Biomaterials Science Année : 2017

Biorthogonal click chemistry on poly(lactic-co-glycolic acid)-polymeric particles

Résumé

Biodegradable polymeric materials are a key area of investigation in drug delivery and disease treatment. This is due to their proven clinical potential for payload protection, responsivity, and surface modification imparted by the versatile array of polymers available for their formulation. Here, we employ a novel biodegradable azide containing polymer in the formulation of polymeric nanoparticles and show that these particles can then be functionalized, with biorthogonal click reactions, to alter their surface appearance and their ability to interact with biological systems.

Domaines

Chimie
Fichier non déposé

Dates et versions

hal-02111568 , version 1 (26-04-2019)

Identifiants

Citer

Jason Olejniczak, Guillaume Collet, Viet Anh Nguyen Huu, Minnie Chan, Sangeun Lee, et al.. Biorthogonal click chemistry on poly(lactic-co-glycolic acid)-polymeric particles. Biomaterials Science, 2017, 5 (2), pp.211-215. ⟨10.1039/C6BM00721J⟩. ⟨hal-02111568⟩
22 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More