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Article Dans Une Revue British Journal of Pharmacology Année : 2010

Gallium modulates osteoclastic bone resorption in vitro without affecting osteoblasts.

Résumé

Gallium (Ga) has been shown to be effective in the treatment of disorders associated with accelerated bone loss, including cancer-related hypercalcemia and Paget's disease. These clinical applications suggest that Ga could reduce bone resorption. However, few studies have studied the effects of Ga on osteoclastic resorption. Here, we have explored the effects of Ga on bone cells in vitro.

Dates et versions

hal-02109579 , version 1 (25-04-2019)

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Citer

Elise Verron, Martial Masson, Solmaz Khoshniat, Laurence Duplomb, Yohann Wittrant, et al.. Gallium modulates osteoclastic bone resorption in vitro without affecting osteoblasts.. British Journal of Pharmacology, 2010, 159 (8), pp.1681-92. ⟨10.1111/j.1476-5381.2010.00665.x⟩. ⟨hal-02109579⟩
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