A novel prototype of calorimetric cell has been developed and the technical details of the system and typical results are presented. It was demonstrated that this invention allows performing experiments under pressure, potentially up to 200bar with an in situ stirring system. The demonstration focuses particularly on the determination of the enthalpy variation and temperature of dissociation of CO2 hydrate and a positive comparison with published data. The use of such a system thus opens a wide range of potential practical applications for determining properties of complex fluids in both pressurized and agitated conditions.