One very popular form of interpersonal interaction used in various situations is the handshake (HS), which is an act that is both physical and social. This article aims to demonstrate that the paradigm of synchrony that refers to the psychology of individuals' temporal movement coordination could also be considered in handshaking. For this purpose, the physical features of the human HS are investigated in two different social situations: greeting and consolation. The duration and frequency of the HS and the force of the grip have been measured and compared using a prototype of a wearable system equipped with several sensors. The results show that an HS can be decomposed into four phases, and after a short physical contact, a synchrony emerges between the two persons who are shaking hands. A statistical analysis conducted on 31 persons showed that, in the two different contexts, there is a significant difference in the duration of HS, but the frequency of motion and time needed to synchronize were not impacted by the context of an interaction.