An enhancer factor defect in a mutant Burkitt lymphoma cell line. - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Journal of Experimental Medicine Année : 1988

An enhancer factor defect in a mutant Burkitt lymphoma cell line.

Résumé

RJ 2.2.5 is an immunoselected mutant of the Burkitt lymphoma line Raji. It fails to display MHC class II antigens at the cell surface due to a transcriptional defect. We have identified the function of a regulatory factor that is defective in RJ 2.2.5 cells; this factor is absolutely required for the activity of an MHC class II gene enhancer.
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Dates et versions

hal-01949126 , version 1 (09-12-2018)

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  • HAL Id : hal-01949126 , version 1
  • PUBMED : 2189699

Citer

Werner Koch, Serge M. Candéias, John Guardiola, Roberto Accolla, Christophe Benoist, et al.. An enhancer factor defect in a mutant Burkitt lymphoma cell line.. Journal of Experimental Medicine, 1988, 167 (6), pp.1781-90. ⟨hal-01949126⟩

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