Major ligand-induced rearrangement of the heptahelical domain interface in a GPCR dimer
Mots clés
Humans
Animals
HEK293 Cells
Protein Binding
Models
Molecular
Rats
Ligands
Transfection
Cercopithecus aethiops
COS Cells
Transcriptional Activation
Mutagenesis
Site-Directed
*Protein Multimerization
Alanine/genetics
Cysteine/genetics
Protein Structure
Tertiary
Protein Subunits
Receptor
Metabotropic Glutamate 5/agonists/chemistry/genetics
Receptors
GABA-B/chemistry/genetics/metabolism
Metabotropic Glutamate/agonists/*chemistry/genetics