Degradation of two hypertensive medicines by hydroxyl and sulfate radicals
Résumé
Losartan Potassium (LP) and Furosemide (FRSM) are consumed mainly by hypertensive patients. Their consumption is predicted to increase in the next years, and thus will they discharge onto surface waters. Therefore, it is important to establish effective treatment technologies for the removal of these compounds in water treatment plants, thus preventing their occurrence in drinking water.
In the present work, quantum yields (Φ254nm) for LP and FRSM were determined. The addition of hydrogen peroxide or persulfate in the irradiation process largely increases the degradation of losartan potassium while the degradation of furosemide is only slightly higher in presence of reactants. TOC degradation was reduced, indicating accumulation of degradation products.