MRI and luminescence detection of Zn{2+}with a lanthanide complex-zinc finger peptide conjugate.
Résumé
A bioinspired probe based on a zinc finger peptide functionalized by a lanthanide(iii)-DOTA monoamide complex turns out to be active for both luminescence and MRI detection of $Zn^{2+}$, depending on the lanthanide cation. A mechanism for MRI-based detection is proposed.