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Article Dans Une Revue Obesity Surgery Année : 2016

Bariatric Surgery Outcomes in Sarcopenic Obesity

Résumé

BACKGROUND: Sarcopenic obesity is the combination of low muscle mass and strength with increased fat mass. This condition is associated with negative health outcomes. We hypothesized that sarcopenia could be a pejorative factor on surgical weight loss. OBJECTIVE: The objectives of the study are to determine the influence of sarcopenic obesity on gastric bypass and sleeve gastrectomy results regarding weight loss and comorbidities resolution at 3, 6, and 12 months. SETTING: The study was conducted at the University Hospital. METHODS: Sixty-nine obese patients who benefited from bariatric surgery were included. Skeletal muscle mass was determined by the Janssen's equation. Physical performance and muscle strength were determined using the 6-min walk test and the wall sit test. Obese subjects from the lowest tertile of the Skeletal Muscle mass Index (SMI) of Baumgartner were set as sarcopenic. RESULTS: Weight loss outcomes and rate of weight loss failure were not influenced by sarcopenia. At 1 year, mean EBMIL% was 75.4 % +/- 5 in sarcopenic subjects vs 67.8 % +/-4 in the non-sarcopenic subjects (p = 0.242). Improvement rates of co-morbidities were similar between groups. Skeletal muscle mass was no more different between groups at 1 year after surgery. There was no patient lost to follow-up. CONCLUSIONS: Bariatric surgery remains effective in achieving weight loss target in sarcopenic patients, with similar remission rates of main comorbidities and similar safety profile than in the non-sarcopenic group. Whether bariatric surgery could result in improvement or deterioration of daily living activities disabilities and functional autonomy in sarcopenic obese patients still have to be evaluated.
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Dates et versions

hal-01850040 , version 1 (26-07-2018)

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D. Mastino, M. Robert, C. Betry, M. Laville, C. Gouillat, et al.. Bariatric Surgery Outcomes in Sarcopenic Obesity. Obesity Surgery, 2016, 26 (10), pp.2355-62. ⟨10.1007/s11695-016-2102-7⟩. ⟨hal-01850040⟩
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