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Article Dans Une Revue Photodiagnosis and Photodynamic Therapy Année : 2016

Iodination improves the phototoxicity of an amphiphilic porphyrin

Résumé

Highlights • A novel tri-iodinated photosensitising porphyrin was designed and synthesized. • The presence of the iodine atom optimize the singlet oxygen generation compared to its non-halogenated analogue. • The phototoxicity of this tri-iodinated amphiphilic porphyrin is significantly improved.
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Dates et versions

hal-01848995 , version 1 (25-07-2018)

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Derya Topkaya, Shie Yin Ng, Yann Bretonnière, Dominique Lafont, Lip Yong Chung, et al.. Iodination improves the phototoxicity of an amphiphilic porphyrin. Photodiagnosis and Photodynamic Therapy, 2016, 16, pp.12 - 14. ⟨10.1016/j.pdpdt.2016.07.008⟩. ⟨hal-01848995⟩

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