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Article Dans Une Revue European Journal of Applied Physiology Année : 2013

Acute supra-therapeutic oral terbutaline administration has no ergogenic effect in non-asthmatic athletes

Résumé

This study aimed to investigate the effects on a possible improvement in aerobic and anaerobic performance of oral terbutaline (TER) at a supra-therapeutic dose in 7 healthy competitive male athletes. On day 1, ventilatory threshold, maximum oxygen uptake and corresponding power output were measured and used to determine the exercise load on days 2 and 3. On days 2 and 3, 8 mg of TER or placebo were orally administered in a double-blind process to athletes who rested for 3 h, and then performed a battery of tests including a force-velocity exercise test, running sprint and a maximal endurance cycling test at Delta 50 % (50 % between VT and ). Lactatemia, anaerobic parameters and endurance performance ( and time until exhaustion) were raised during the corresponding tests. We found that TER administration did not improve any of the parameters of aerobic performance (p > 0.05). In addition, no change in kinetic parameters was found with TER compared to placebo (p > 0.05). Moreover, no enhancement of the force-velocity relationship was observed during sprint exercises after TER intake (p > 0.05) and, on the contrary, maximal strength decreased significantly after TER intake (p < 0.05) but maximal power remained unchanged (p > 0.05). In conclusion, oral acute administration of TER at a supra-therapeutic dose seems to be without any relevant ergogenic effect on anaerobic and aerobic performances in healthy athletes. However, all participants experienced adverse side effects such as tremors.

Dates et versions

hal-01837561 , version 1 (12-07-2018)

Identifiants

Citer

Anthony Sanchez, Fabio Borrani, Marie Amelie Le Fur, Anais Le Mieux, Virgile Lecoultre, et al.. Acute supra-therapeutic oral terbutaline administration has no ergogenic effect in non-asthmatic athletes. European Journal of Applied Physiology, 2013, 113 (2), pp.411 - 418. ⟨10.1007/s00421-012-2447-0⟩. ⟨hal-01837561⟩
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