Organomagnesiate-Promoted Enantioselective Cascade Process: Straightforward Access to Chiral 3-Substituted Isobenzofuranones
Résumé
The bimetallic organomagnesiate ate complex (S)-(BIPHEN)BuMgLi is reported here as a dual efficient halogen-metal exchange and chirality transfer agent in the reaction of ethyl-2-iodobenzoate with aldehydes leading to the formation of various chiral 3-substituted isobenzofuranones in good yields and enantiomeric ratios.
Domaines
Chimie organique| Origine | Fichiers produits par l'(les) auteur(s) |
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