Management of uveomeningitis in internal medicine: Proposal for a diagnostic work-up - Archive ouverte HAL Access content directly
Journal Articles La Revue de Médecine Interne Year : 2016

Management of uveomeningitis in internal medicine: Proposal for a diagnostic work-up

S. Abad
  • Function : Author
C. Terrada
  • Function : Author
S. Trad
  • Function : Author
D. Sene
  • Function : Author
P. Bielefeld
  • Function : Author
D. Saadoun
  • Function : Author

Abstract

Uveomeningitis relates to an inflammatory state extending from iris and ciliary bodies to the choroid behind the eye. Because of a close contact between eye and brain, and barrier disruption, the inflammation can spread into the central nervous system (CNS). We review the clinical manifestations of uveitis, which are known to provide helpful clues to the diagnosis and describe the infectious, inflammatory, and neoplastic conditions classically associated with the uveomeningitis. Inflammatory or auto-immune diseases are probably the most common clinically recognized causes of uveomeningitis associated with a significant pleiocytosis. These entities often cause inflammation of various tissues in the body, including ocular structures and the meninges (i.e., sarcoidosis, Behcet's disease, and Vogt-Koyanagi-Harada syndrome). The association of an infectious uveitis with an acute or a chronic meningo-encephalitis is unusual but occasionally the eye examination may suggest an infectious etiology or even a specific organism responsible for an uveomeningitis. One should consider the diagnosis of primary ocular-CNS lymphoma in patients of 40 years of age or older with bilateral uveitis, especially with prominent vitritis, showing poor response to corticosteroid therapy. Finally, an algorithm for the diagnostic approach of uveomeningitis is proposed
No file

Dates and versions

hal-01791293 , version 1 (14-05-2018)

Identifiers

Cite

S. Abad, C. Terrada, S. Trad, D. Sene, P. Bielefeld, et al.. Management of uveomeningitis in internal medicine: Proposal for a diagnostic work-up. La Revue de Médecine Interne, 2016, 37, pp.25-34. ⟨10.1016/j.revmed.2015.09.009⟩. ⟨hal-01791293⟩
25 View
0 Download

Altmetric

Share

Gmail Facebook X LinkedIn More