Enhancement of Corneal Visibility in Optical Coherence Tomography Images using Corneal Adaptive Compensation - Archive ouverte HAL
Journal Articles Translational vision science & technology Year : 2015

Enhancement of Corneal Visibility in Optical Coherence Tomography Images using Corneal Adaptive Compensation

Marcus Ang
  • Function : Author
Cheuk Wang Chung
  • Function : Author
Mohamed Farook
  • Function : Author
Nicholas G. Strouthidis
  • Function : Author
  • PersonId : 869280
Joddhbir S. Mehta
  • Function : Author
Jean-Martial Mari

Abstract

Purpose: To improve the contrast of optical coherence tomography (OCT) images of the cornea (post processing). Methods: We have recently developed standard compensation (SC) algorithms to remove light attenuation artifacts. A more recent approach, namely adaptive compensation (AC), further limited noise overamplification within deep tissue regions. AC was shown to work efficiently when all A-scan signals were fully attenuated at high depth. But in many imaging applications (e.g., OCT imaging of the cornea), such an assumption is not satisfied, which can result in strong noise overamplification. A corneal adaptive compensation (CAC) algorithm was therefore developed to overcome such limitation. CAC benefited from local A-scan processing (rather than global as in AC) and its performance was compared with that of SC and AC using Fourier-domain OCT images of four human corneas. Results: CAC provided considerably superior image contrast improvement than SC or AC did, with excellent visibility of the corneal stroma, low noise overamplification, homogeneous signal amplification, and high contrast. Specifically, CAC provided mean interlayer contrasts (a measure of high stromal visibility and low noise) greater than 0.97, while SC and AC provided lower values ranging from 0.38 to 1.00. Conclusion: CAC provided considerable improvement compared with SC and AC by eliminating noise overamplification, while maintaining all benefits of compensation, thus making the corneal endothelium and corneal thickness easily identifiable.
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Dates and versions

hal-01711230 , version 1 (16-02-2018)

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Michaël J. A. Girard, Marcus Ang, Cheuk Wang Chung, Mohamed Farook, Nicholas G. Strouthidis, et al.. Enhancement of Corneal Visibility in Optical Coherence Tomography Images using Corneal Adaptive Compensation. Translational vision science & technology, 2015, 4 (3), ⟨10.1167/tvst.4.3.3⟩. ⟨hal-01711230⟩

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