An efficient synthesis of anhydrides of 2-monosubstituted succinic acid monoesters and their application to the Dakin–West reaction: Isolation of some 5-succinyloxyoxazole intermediates - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Letters in Peptide Science Année : 1998

An efficient synthesis of anhydrides of 2-monosubstituted succinic acid monoesters and their application to the Dakin–West reaction: Isolation of some 5-succinyloxyoxazole intermediates

Résumé

A rapid and versatile synthesis of 2-monosubstituted monosuccinates and their bimolecular anhydrides is described. The reaction of these anhydrides with N-Fmoc-protected dipeptides under the modified Dakin–West reaction affords mainly the corresponding 5-succinyloxyoxazoles

Dates et versions

hal-01709911 , version 1 (15-02-2018)

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Joseph Richard Casimir, Laurent Ettouati, Joëlle Paris. An efficient synthesis of anhydrides of 2-monosubstituted succinic acid monoesters and their application to the Dakin–West reaction: Isolation of some 5-succinyloxyoxazole intermediates. Letters in Peptide Science, 1998, 5 (1), pp.13-18. ⟨10.1023/A:1008847624738⟩. ⟨hal-01709911⟩

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