New application of the Julia olefination for the synthesis of Tyr-Gly E-alkene and carba isostere pseudopeptides
Résumé
A new application of the Julia olefination to the synthesis of TyrΨ[E-CH=CH]Gly and TyrΨCH2CH2]Gly pseudopeptides is described via condensation of tertiobutyl bromoacetate on tyrosine-derived β-ketosulfone and subsequent reductive desulfonation
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