Correlation between fluorodeoxyglucose hotspots on pretreatment positron emission tomography/CT and preferential sites of local relapse after chemoradiotherapy for head and neck squamous cell carcinoma - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Archives of Otorhinolaryngology - Head & Neck Surgery Année : 2017

Correlation between fluorodeoxyglucose hotspots on pretreatment positron emission tomography/CT and preferential sites of local relapse after chemoradiotherapy for head and neck squamous cell carcinoma

Résumé

The potential benefits of (18) F-fluoro-2-deoxy-D-glucose-positron emission tomography/CT (FDG-PET/CT) imaging for radiotherapy (RT) treatment planning of head and neck squamous cell carcinoma (HNSCC) are increasingly being recognized. It has been suggested that intratumoral subvolumes with high FDG avidity ("hotspots") are potential targets for selected dose escalation. The purposes of this study were to demonstrate that pre-RT FDG-PET/CT can identify intratumoral sites at increased risk of local relapse after RT and to determine an optimal threshold to delineate smaller RT target volumes that would facilitate RT dose escalation without impaired tolerance.
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Dates et versions

hal-01643973 , version 1 (21-11-2017)

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Anne Chaput, Jérémie Calais, Philippe Robin, Sébastien Thureau, David Bourhis, et al.. Correlation between fluorodeoxyglucose hotspots on pretreatment positron emission tomography/CT and preferential sites of local relapse after chemoradiotherapy for head and neck squamous cell carcinoma. Archives of Otorhinolaryngology - Head & Neck Surgery, 2017, 39 (6), pp.1155 - 1165. ⟨10.1002/hed.24738⟩. ⟨hal-01643973⟩
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