In the present paper, an experimental procedure is proposed to measure the total heat of sorption between a solvent and an absorbent The method uses a thermogravimetric balance coupled with a differential scanning calorimeter. The calorimetric signal and the DTG signal are used in a simple model to determine a continuous expression of the total heat of sorption vs. the solvent mass content. The method is rapid and convenient for complex heterogeneous sorbents like foodstuff or sludge. Validation of the method for the couple microcrystalline cellulose - water is presented.