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Chapitre D'ouvrage Année : 2016

Exercise and the Hypothalamo-Pituitary-Adrenal Axis

Résumé

Exercise represents a potent physiological stimulus upon the hypothalamo-pituitary adrenal (HPA) axis. Two major factors modulate the HPA axis response to exercise: intensity and duration. Endurance training per se does not induce permanent hypercortisolism as endurance-trained subjects have similar biological markers of HPA axis activity in resting condition as healthy untrained men. However, during a challenge of the HPA axis, endurance-trained subjects demonstrate an adaptation of the HPA axis activity to repeated exercise resulting from decreased tissular sensitivity to glucocorticoids. A great diversity of other mechanisms is involved in this adaptation, acting potentially at all levels in the cascade and leading to the biological effects of cortisol

Dates et versions

hal-01606607 , version 1 (02-10-2017)

Identifiants

Citer

Martine Duclos, Antoine Tabarin. Exercise and the Hypothalamo-Pituitary-Adrenal Axis. Sports Endocrinology, 47, Karger, 172 p., 2016, Frontiers of Hormone Research, 978-3-318-05869-7; 978-3-318-05868-0. ⟨10.1159/000445149⟩. ⟨hal-01606607⟩
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