Article Dans Une Revue Correspondances en Métabolismes, Hormones, Diabètes et Nutrition Année : 2015

Microbiote, alcool et foie

Résumé

Alcoholic liver disease can be divided into overlapping phases with distinct pathological and clinical features. The severe stages, including acute steatohepatitis and cirrhosis, are associated with a high mortality risk. Alcohol consumption together with gut microbiota activity increase gut permeability, leading to the passage of bacterial components which may trigger liver inflammation. Alcohol consumption is thought to change gut microbiota composition. However, only a fraction of alcoholic patients display a dysbiosis, associated with increased gut permeability. Probiotic treatments have been proven to reduce alcohol-induced liver injury in animal models and in humans.

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Dates et versions

hal-01536497 , version 1 (11-06-2017)

Identifiants

  • HAL Id : hal-01536497 , version 1
  • PRODINRA : 333815
  • WOS : 000357055500005

Citer

Philippe Gerard. Microbiote, alcool et foie. Correspondances en Métabolismes, Hormones, Diabètes et Nutrition, 2015, 19 (6), pp.142-144. ⟨hal-01536497⟩
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