SYNCHROTRON RADIATION PHASE CT FOR THE INVESTIGATION OF NANO PROPERTIES IN FEMORAL HUMAN BONE
Résumé
The mechanisms of bone fragility in relation to diseases such as osteoporosis remain only partially understood. Extensive attention has been devoted to the osteocyte cell network, which plays a central role in bone remodeling, but for which observation remains challenging. To assess bone nano-structure, we propose to use a new 3D X-ray phase nano-CT setup developed at the ESRF (European Synchrotron Radiation Facility) in Grenoble, which targets to reach isotropic spatial resolution up to 20 nm. Images of cortical bone samples with isotropic voxel size of 120nm, 50nm and 30nm are presented.
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