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Article Dans Une Revue Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment Année : 2017

Construction and tests of an in-beam PET-like demonstrator for hadrontherapy beam ballistic control

Résumé

We present the first results obtained with a detector, called Large Area Pixelized Detector (LAPD), dedicated to the study the ballistic control of the beam delivered to the patient by in-beam and real time detection of secondary particles, emitted during its irradiation in the context of hadrontherapy. These particles are 511 keV γ from the annihilation of a positron issued from the β+ emitters induced in the patient tissues along the beam path. The LAPD basic concepts are similar to a conventional PET camera. The 511 keV γ are detected and the reconstructed lines of response allow to measure the β+ activity distribution. Nevertheless, when trying to use γ from positron annihilation for the ballistic control in hadrontherapy, the large prompt γ background should be taken into account and properly rejected. First reconstruction results, obtained with a phantom filled with a high intensity FDG source at the cancer research centre of Clermont-Ferrand are shown. We also report results of measurements performed at the Heidelberg Ion-Beam Therapy Centre with one third of the detector, using proton and carbon ion beams.
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Dates et versions

hal-01478282 , version 1 (28-02-2017)

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G. Montarou, M. Bony, E. Busato, R. Chadelas, D. Donnarieix, et al.. Construction and tests of an in-beam PET-like demonstrator for hadrontherapy beam ballistic control. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2017, 845, pp.673 - 678. ⟨10.1016/j.nima.2016.04.106⟩. ⟨hal-01478282⟩
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